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What Happens If ADHD is Left Untreated in Adults? Untreated ADHD can lead to a myriad of problems for adults. These can include issues with relationships, work, and mental health. Often, adults with untreated ADHD have low self-esteem and a negative perception of the world. This can cause them to feel like they're failing both at work and at home. Lack of Focus Finding it difficult to stay focused at times is normal and is commonplace, especially after a tiring day at work or school. If, however, you begin to notice that your focus has been decreasing and it's im