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Our secondary aim was to explore the results of autoimmune comorbidities on achalasia phenotype (clinical features and manometric pattern). The research population contained 375 successive patients (215 females-median age 55 ± 17years), referred at our tertiary referral center from January 2008 to January 2018, with clinical and instrumental (EGDS, barium esophagogram, and manometry) analysis of idiopathic achalasia. Gender- and age-matched subjects undergoing manometry and pH-impedance monito