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This study aimed to evaluate the risk of sustained life-threatening ventricular tachyarrhythmias (VTAs) after hospitalization for heart failure (HHF). HHF is common among patients with an implantable cardioverter-defibrillator (ICD). We analyzed all 5,511 ICD patients enrolled in the landmark MADIT and RAID trials. Multivariate Cox regression was used to evaluate the association of in-trial HHF occurrence with the risk of subsequent VTA and the composite end point of VTA or cardiac death. Mean age was 64 ± 11 years, 23% were women, 62%