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Diagnosis was the main predictor of cognitive fatigue (p less then .001, ηp2 = 0.178), followed by depression (p = .010, ηp2 = 0.08. Survivors of BT reported significantly more fatigue than healthy controls on all fatigue subscales. While they also expressed more symptoms of depression, we found no evidence for an interaction effect. Parent-child concordance was moderate to good among survivors, but poor for controls. CONCLUSIONS Survivors of BT and ALL suffer from cognitive fatigue, with survivors of BT expressing more problems. Co