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ADHD OTC Medication The majority of children and adults who take ADHD medication will experience a few side effects. These usually include loss of appetite as well as stomach upsets and changes in heart rate. These side effects can be minimized through a balanced diet and sufficient sleep. Stimulants boost the communication between brain cells, which helps children focus and manage impulses. They can also cause tics or increase blood pressure. These are controlled substances that can be crushed or inhaled t