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(1) Background To examine the prevalence, and associated factors of, problematic Internet use in a sample of Spanish university students. (2) Methods Cross-sectional descriptive study of a convenience sample of 698 university students. Self-esteem, alcohol consumption, perceived social support, depression, anxiety, stress and problematic Internet use were evaluated using the Rosenberg, CAGE, DUKE-UNC-11, DASS-21 and Young's Internet Addiction Test, respectively. (3) Results Problematic internet use was reported by 21% of respondents. Ris