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level of PH-related genes. Our findings provide new insights into the impact of postnatal hypoxia and the role of m A in the development of pulmonary vascular pathophysiology. Our results indicate postnatal hypoxia can cause PH, which can persist into adulthood. The development and persistence of PH may be because of the continuous low expression of methyltransferase like 3 affecting the m6A level of PH-related genes. Our findings provide new insights into the impact of postnatal hypoxia and the role of m6A in the development of pulmona