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Consequently, we evaluated the in vivo results of the concomitant administration of LCL-PLP and liposomal formulation of DOX (LCL-DOX) on B16.F10 melanoma growth and on the production of crucial molecular markers for cyst development. Our outcomes demonstrated that the concomitant administration of LCL-PLP and LCL-DOX induced a very good inhibition of tumefaction growth, mainly by inhibiting TAMs-mediated angiogenesis along with the tumor production of MMP-2 and AP-1. More over,
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