https://betaamyloid-signal.com/editorial
Siderophores help to transfer iron. Type 2-hydroxybutyrate dehydrogenase (BDH2) is a rate-limiting aspect in the biogenesis of siderophores. Utilizing qRT-PCR, we evaluate BDH2mRNA expression in the bone marrow (BM) of 187 MDS clients, 119 de novo intense myeloid leukemia (AML) clients, and 43 lymphoma patients with normal BM. Elevated BDH2mRNA phrase in BM is observed in MDS patients (n = 187 vs. 43, typical BM; P = 0.009), and this relates to ferritin levels. Customers with higher BDH2 expression reveal a better risk of leukemia development (1
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