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Functionalized MWCNTs induced higher time- and dose-dependent toxic effects as compared to pristine. The SEM observations revealed the damaging effect on the cell membrane, offering insights about the toxic mechanism that takes place. Both di(2-ethylhexyl)phthalate (DEHP) and ethanol have toxic effects on the liver, and the oral exposure to DEHP in combination with ethanol may exist in the alcohol consumers, however, current food safety risk assessments based solely on the toxicity data of DEHP may underestimate the health impacts of phtha