https://www.selleckchem.com/products/azd8186.html
Low culture temperature is known to enhance the cell-specific productivity of CHO cells expressing varied recombinant (r-) proteins, but the mechanisms remain unclear. Regulation of UPR pathway genes, such as transcriptional regulatory factors and ER-resident proteins, appear to be involved in the improvements of r-protein production under low temperature conditions. We studied the transcriptional regulation of UPR-specific targets in response to decreased culture temperature in relation to production of a difficult-to-express (DTE) pro
Like
Comment
Share
