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ADHD Medication - Choosing the Right One Medication is an important element of ADHD treatment. Finding the right medication may take a long time, as different medications affect people differently. Stimulants raise levels of brain chemicals that aid in focusing and controlling impulses. They can also trigger side effects like shaky hands, stomach discomfort and an increase in heart rate. Stimulants Stimulants are drugs that "stimulate" brain processes and activity. They can boost concentration, alertness, and energy and help improve focus.