https://www.selleckchem.com/pr....oducts/alkbh5-inhibi
Results The results showed that BMSCs caused significant decreases in telomere length, telomerase activity, and the mRNA level of hTERT as a regulator of telomerase activity. The significant presence of interleukin (IL)-6, IL-8, and transforming growth factor beta (TGF-β) was obvious in the co-cultured media. Also, BMSCs significantly decreased and increased the gene and protein expression of β-catenin and P53, respectively. Conclusion It was concluded that the mentioned effects of IL-6, IL-8, and TGF-β cytokines secreted fro