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INTERVENTIONS The patient underwent left temporal and parietal lesions total resection with a craniotomy. OUTCOMES The diagnosis of PDLM was established according to pathological characteristics and the negative finding of positron emission tomography (PET)-computed tomography (CT) outside CNS. The patient got no further treatment for economic reasons and experienced the progression and died 5 months after operation. LESSONS PDLM is extremely rare in CNS, as the clinical manifestation, radiological changes are not special, early diagnos