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No significant pre- to post-exercise increase in neurotrophic factors (p 0.05; BDNF; effect size = 0.46 and NGF; effect size = 0.48) was observed for either of the RT bouts. A similar increase in blood lactate concentration was observed pre- to post-exercise for both RT bouts (p less then 0.05). Cortisol increased similarly for both RT bouts, when compared to the resting day condition (p less then 0.05). In conclusion, the results suggest that, despite differences in RT schemes, a similar acute neurotrophic, metabolic and hormonal res