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Treatments For ADHD in Adults The same methods that work for children can also help adults manage their ADHD symptoms. They include therapy, medicine as well as various strategies for coping and coaching. Methylphenidate (MPH) is the most frequently used medication to treat adult ADHD. This class of drugs is effective by increasing the activity in specific regions of the brain that control behavior and attention. Stimulant Medication Stimulant medication is the foundatio