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Higher electronic properties (topological polar surface area of 10 along with lesser steric properties (molar volume less then 300 cm3) of the compounds compared to the standard supported their significant anti-inflammatory potential. Additionally, procerolide B exhibited comparatively lesser binding energy with aminoacyl residues of cyclooxygenase-2 (-9.82 kcal/mol) thereby recognizing its prospective therapeutic use against inflammatory pathogenesis.The alfalfa plant bug Adelphocoris lineolatus, an economically important pest, ha