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Immunohistochemically, the estrogen-negative, CK7-positive, C-erb B2-positive intralymphatic metastases were associated with extensive infiltration of CD8-positive cytototoxic T lymphocytes. Factors that may have precluded the implantation of intralymphatic metastases leading to SR are discussed, with local immune surveillance being one major hypothesis. © 2020 John Wiley Sons A/S. Published by John Wiley Sons Ltd.BACKGROUND Eccrine duct dilatation (EDD) has been noted to occur significantly more often in primary lymphoc