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Adult ADHD and Comorbid Disorders Many adults suffering from ADHD also suffer from comorbid disorders such as major depression (Kessler and colleagues 2006). Many sufferers do not respond to medication for depression and may be able to benefit from psychotherapy. Neurotransmitters are brain chemicals that regulate and boost levels of certain brain chemicals. The stimulants methylphenidate and amphetamine are frequently prescribed. Medicines Adults can tak