https://cc220chemical.com/mana....ging-the-effectivene
Here, the importance of the heterocyclic core in the cell death modulating results associated with telmisartan-derived lead 4'-((2-propyl-1 H -benzo[ d ]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid ended up being examined. Inspired by the pharmacodynamics of HYL-6d in addition to selective PPARγ ligand VSP-51, the benzimidazole was replaced by a carbazole or an indole core . The outcomes suggest no correlation between PPARγ activation and sensitization of resistant CML cell
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