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The morphology change makes the hybrid a perfect applicant for application in a precisely controlled medicine delivery process. It could unexpectedly act as a photosensitizer and a carrier for enantioselective absorption of particular chiral medicines enantiomer (l-dopa and S-naproxen salt) also display on-demand drug release as a result of helix reversal induced by light irradiation. Our results illustrate how the surface reactivity can direct the helical organization of adsorbe