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This reduction in reward involves activation of GLP-1 receptors (GLP-1R) within areas processing natural and synthetic rewards, like the laterodorsal tegmental area (LDTg), ventral tegmental area (VTA) and nucleus accumbens (NAc) layer. These places are part of a neurocircuitry mediating reward from addictive medications and natural incentives including intimate behaviors. The male intimate encounter with a lady includes three different stages a pre-sexual interacting with each other phase with persona
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