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The weighted DEGs have biological importance produced from the gene regulatory network. On the basis of the weighted DEGs, five binary classifiers had been discovered and demonstrated great performance regarding the "Sensitivity," "Specificity," "Accuracy," "F1," and "AUC" metrics. The GOEGCN with weighted DEGs for control and experiment teams provided a novel GO enrichment analysis results plus the novel enriched GO terms would further unveil the modifications of specific biological