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The lymphatic invasion ended up being detected in 8% of situations by HE staining and 23% of instances with D2-40 immunostaining. Only D2-40-detected lymphatic invasion showed a statistically significant relationship with colorectal cancer-specific death using univariate analysis (p=0.01). Survival analysis carried out independently by Cox regression demonstrated that lymphatic invasion recognized by D2-40 immunostaining ended up being involving even worse disease-specific survival (risk