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Medication For Autism and ADHD Many adults and children with autism use psychotropic medication. Certain medications can help reduce the intensity of irritability and disruptive behaviors that are sometimes associated with ADHD. The medication for ADHD can improve core symptoms of Autism, and decrease hyperactivity and impulsivity. They can also help reduce problematic behaviors like aggression, self-injury, licking and picking as well as trichotillomania and obsessive-compulsive symptoms