https://www.selleckchem.com/pr....oducts/brefeldin-a.h
Antibiotic resistance is rising and we urgently need to gain a better quantitative understanding of how antibiotics act, which in turn would also speed up the development of new antibiotics. Here, we describe a computational model (COMBAT-COmputational Model of Bacterial Antibiotic Target-binding) that can quantitatively predict antibiotic dose-response relationships. Our goal is dual We address a fundamental biological question and investigate how drug-target binding shapes antibiotic action. We also create a tool that can predict
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