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In-source fragmentswere found to be more suitable than their parent pesticides as precursor ions for MRM analysis. The aim of this study was to analyse use of and adherence to influenza and pneumococcal vaccination in high-risk patients with chronic pulmonary disease. The study was initiated at the Centre of Pneumology in Donaustauf, Germany. All patients with asthma bronchiale (A, chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) that were treated in a pneumological Non-ICU ward, in the sleep laboratory or in the outpatient