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© 2020 Leal et al.Background Mastitis is one of the most typical infectious conditions in milk cattle and causes considerable financial losings in the milk industry all over the world. Antibiotic treatment has been utilized as the utmost effective technique for clinical mastitis treatment. But, as a result of extensive usage of anti-bacterial representatives, antimicrobial weight (AMR) is considered becoming a primary reason for reduced cure rates in bovine mastitis. In addition, biofilms could pro