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Using the electron density and its associated quantities in a molecular system to quantify chemical reactivity in density functional theory is of considerable recent interest. Local temperature based on the kinetic energy density is an intrinsic property of a molecular system, which can be employed for this purpose. In this work, we explore such a possibility. To this end, we examine the local behavior of local temperature with a few choices of the kinetic energy density, apply it to determine regioselectivity of nucleophilic and electro