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The biosynthesis of these two compounds was also induced by another HDAC inhibitor, trichostatin A. These results demonstrate the usefulness of HDAC inhibitors to activate cryptic secondary metabolite biosynthesis in cultured plant cells. In cranio-maxillofacial surgery, it is of great clinical significance to segment mandible accurately and automatically from CT images. However, the connected region and blurred boundary in teeth and condyles make the process challenging. At present, the mandible is commonly segmented by experienced doct