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How Does Medication For ADHD Work? Stimulants boost the levels of dopamine and norepinephrine within your brain, helping improve the ability to focus and control impulses. They are available in immediate-release (short acting) and extended release tablets. They can be taken daily in the morning. Nonstimulant medicines are more difficult to use but they can improve the ability to control impulses and attention. Atomoxetine, Viloxazine and guanfacine are antidepressants that boost norepinephrine levels. Stimu