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Here we present 2 situations of diagnosed medulloblastoma which on re-resection had been noted to be gangliocytoma without heterogeneity, which will be an incredibly unusual incident. 1st client, an 11-year-old son identified as having high-risk (non-WNT, non-SHH) medulloblastoma, had been addressed with near-total medical resection followed by craniospinal radiotherapy with weekly vincristine. Then received upkeep chemotherapy with vincristine, cyclophosphamide, and cisplatin