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STUDY DESIGN Cross-sectional. OBJECTIVES To investigate factors influencing depressed mood in individuals with traumatic spinal cord injury (TSCI) and caregivers' perceived burden in a low-income country. SETTING Dhulikhel Hospital and Spinal Injury Rehabilitation Center, Nepal. METHODS We recruited 95 couples (one person with spinal cord injury and one caregiver) aged 18-65 years. Participants with various levels and types of TSCI with post-injury duration of or providing care for ≥1 month were eligible for the study. The Nepali Beck Depress