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Results We described for the first time the kinetics of T cellular response during the clinical length of DENV disease. Serious cases revealed notably reduced amounts of effector CD8+ T cells when compared with moderate situations at day -1 (p = 0.017) and day 0 (p = 0.033) of defervescence. After defervescence, these cell matters in serious instances enhanced rapidly to equalize aided by the amounts of mild cases. Our results also revealed a decline in complete CD4+ T, Th1, Th1/17