https://www.selleckchem.com/pr....oducts/poly-d-lysine
y across subgroups paves the way for osimertinib-based combinations, which are being investigated in ongoing trials.Huntington disease (HD) manifests a unique macroautophagy/autophagy defect the presense of cytosolic autophagosomes without substrates or so-called "empty" autophagosomes. It was proposed that mutant HTT (huntingtin; mHTT) disrupts cargo recognition by the selective autophagy receptor SQSTM1/p62 thus leading to the failure of cargo sequestration by phagophores, the precursors to autophagosomes. Here we l