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in contrast to other concentrations into the skin defect model. When it comes to bone exposed model, 0.5, 1, and 2 mM EDTA-NS had reduced prices of illness and positive countries. For intra-articular implant designs 10 and 50 mM, EDTA-NS had the cheapest rates of infection and good cultures. The levels of EDTA-NS below 10 mM are safe for irrigation. The optimal focus of EDTA-NS differs by type of injury after experimental inoculation of three forms of wound. Cite this article The concentrations of