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agreement between our modelled estimates and the reported data (Pearson's correlation coefficient = .75). CONCLUSION Our modelled estimates generally correspond to estimates observed in the literature, with a few exceptions. These estimates can serve as useful inputs for planning and prioritizing appropriate health interventions for childhood diarrheal diseases in LMICs in the absence of empirical data.BACKGROUND The endocannabinoid system (ECS) overactivation, associated with increased inflammatory process, may act as a risk