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© The Author(s) 2020. Published by Oxford University Press in association with the International Society for Quality in Health Care. All rights reserved. For permissions, please e-mail [email protected] recent description of the polychromatic sponge Plakina kanaky revealed original microsymbionts, with some morphotypes recorded for the first time in Homoscleromorpha, and others never before observed in other sponge groups. Illumina 16S amplicon sequencing was used to characterize this microbial community by comparing co