https://www.selleckchem.com/pr....oducts/Temsirolimus.
In addition, CSC‑like properties, including the expression of CD133, CD44, sex determining region Y‑box 2, Nanog and octamer‑binding transcription factor 4, were markedly decreased in the A549 and H1299 sphere cells following knockdown of CLOCK. Epigallocatechin‑3‑gallate (EGCG), a green tea polyphenol, has been reported to be a potential anticancer phytochemical. EGCG was found to repress CLOCK expression in A549 and H1299 sphere cells. In addition, EGCG also decreased the ratio of CD133+ cells. The Wnt/β‑catenin pathway was notab