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We performed a retrospective study of 127 topics treated for DME with three consecutive treatments of anti-VEGF representatives. Customers' retinas were imaged utilizing spectral-domain OCT (SD-OCT) before and after anti-VEGF treatment, additionally the complete retinal thicknesses pre and post therapy had been obtained from OCT B-scans. A novel deep convolutional neural network was designed and examined using pre-treatment OCT scans as input and differential retinal thickneof America under the terms of the