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Aldolase C/Zebrin II is a brain-type isozyme and is a fructose-1,6-bisphosphate aldolase. In our research, we first utilized immunohistochemistry to verify that aldolase C ended up being produced in the anterior pituitary of rats. Additionally, utilizing transgenic rats revealing green fluorescent protein underneath the control of the S100β gene promoter, we identified aldolase C-immunoreactive indicators in folliculo-stellate cells and limited cells located in the pare