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95 in each cohort. White matter-like and gray matter-like compartments both demonstrated very high reliability in the immediate cohort (both ICC 0.9; however, this declined in the 3-month interval cohort to both compartments having ICC 0.80. Regional CSF-like signal fraction was examined in bilateral hippocampus and had an ICC 0.80 in each cohort. CONCLUSION The three-tissue constrained spherical deconvolution techniques provide reliable and stable estimates of tissue-microstructure composition, up to 3 months longitudin
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