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Overall, our study findings were similar to the reported results in the other reviewed studies, showing that Tc-99m-EC can be considered as an alternative for DMSA scintigraphy, providing interchangeable results. To establish the most appropriate ordered subset expectation maximization (OSEM) parameters for image reconstruction in Tc-99m methoxyisobutylisonitrile (MIBI) myocardial perfusion SPECT (MPS) and comparison with corresponding filtered back projection (FBP)-reconstructed images. A total of 99 stress-rest MPS studies (47 normal a