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How to Choose the Best ADHD Medication for Adults The most frequently prescribed medication by healthcare professionals to treat ADHD is stimulants. They boost levels of dopamine and norepinephrine neurotransmitters in the brain to improve concentration and decrease the risk of impulsive behavior. You can purchase them as liquid or long-acting capsules, or tablets that release immediately (like Dynavel XR). Long-acting stimulants are less likely to be abused. Stimulants Stimulants are the first medications doc