https://www.selleckchem.com/pr....oducts/incb28060.htm
However, the high PAI-1 group had significantly lower values for intensive care unit-free days ( =0.01), continuous renal replacement therapy-free days ( =0.02), and catecholamine-free days ( =0.02). The high PAI-1 group also had a significantly lower 28-day survival rate based on the Kaplan-Meier analysis (log-rank, =0.03). Patients with sepsis and PAI-1 levels of ≥83ng/mL had elevated risks of coagulopathy, organ failure, and mortality. Thus, these results suggest that 83ng/mL could be a useful cut-off value for prognostication base