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TiO2 hollow nanosphere (HNS) are prepared via NaCl templates in a one-pot approach. The NaCl templates are realized by solvent/anti-solvent strategies and coated with TiO2via controlled hydrolysis of Ti-alkoxides. The NaCl template can be easily removed by washing with water, and the TiO2 HNS are finally impregnated with Pd/Pt. Electron microscopy shows TiO2 HNS with an outer diameter of 140-180 nm, an inner cavity of 80-100 nm, and a wall thickness of 30-40 nm. The TiO2 HNS exhibit high surface area (up to 370 m2 g-1)