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Additionally, we found that hexahydrocurcumin therapy could decrease interleukin-6 levels by attenuating p65 of atomic factor kappa-light-chain-enhancer (NF-κ of triggered beta cells. In addition, hexahydrocurcumin additionally decreased oxidative stress, because demonstrated by the expression of 4-hydroxynonenal and thereby avoided apoptosis. Consequently, our finding shows that hexahydrocurcumin prevents dexamethasone-induced AD-like pathology and improves memory impairment.Although the