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The tumor-promoting effect of circ-NOLC1 was inhibited by knockdown of ESRP1, CDK1, or RhoA phrase in circ-NOLC1-overexpressing cells, that might work by modulating RhoA and CDK1 expression. In conclusion, our research demonstrated that Circ-NOLC1 might advertise EOC tumorigenesis and development by binding ESRP1 and modulating CDK1 and RhoA expression.Glioblastoma multiforme (GBM) brings severe actual and mental pain to GBM patients, whose survival rate r