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Histoplasmosis antigen testing ended up being positive in three of four submitted samples. Initial treatment plan for all cats included fluconazole (median dose 26mg/kg/d). Median duration of followup was 11months (range 1-108months; n=4). Resolution of ocular adnexal lesions had been accomplished in three kitties. Two kitties had relapse of disease, one of that was subsequently euthanized. One cat with concurrent feline immunodeficiency virus (FIV) infection passed away a month