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70, P 0.001) in comparing CGITA vs. LIFEx, and CGITA vs. Metavol. Some texture discrepancies across software packages exist. Our findings reinforce the need to continue the standardization process, and to succeed in building a reference dataset to be used for comparisons. Some texture discrepancies across software packages exist. Our findings reinforce the need to continue the standardization process, and to succeed in building a reference dataset to be used for comparisons.Heart failure (HF) is the only cardiovascular disease with